Duration 21:35

(1/3) The Science of Regenerating Teeth and Restoring Smiles — Dr. Paul Sharpe and Further Health

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Published 22 Sep 2021

Donate to help accelerate amazing research projects and improve lives: https://www.every.org/furtherhealth/f/help-create-the-future For all questions related to Biotooth and Dr. Sharpe's work please contact our team directly: https://bit.ly/3tHEIKR Comments are turned off for our videos. ▬ Contents of this video ▬▬▬▬▬▬▬▬▬▬ 0:00 - Intro 0:34 - One Billion People 3:09 - Welcome Dr. Paul Sharpe 4:20 - How Biotooth Started 5:16 - How Biotooth Works 9:40 - Biotooth Proof-of-Concept 11:00 - How Biotooth Becomes a Treatment - The Core Challenge 16:30 - The Impact and Aim of Biotooth Overview: When we talk about living healthier for longer we must also include oral health, which plays a crucially important role in physical and mental health. According to the World Health Organization, over a BILLION people worldwide experience trauma to their teeth at some point in their life, which can lead to tooth loss and lower quality of life. This affects 20% of the human population. Current treatments are costly, lengthy, and often require additional procedures throughout the patient's life, which can be financially and emotionally draining. But what if there were a better way? What if there were a way to regenerate a lost tooth, biologically? What if this biological tooth regeneration technology could replace artificial dental treatments with the real thing? Scientists working on the Biotooth technology aim to create a treatment that could regenerate your damaged or lost tooth using your stem cells. We talk all about Biotooth with none other than Dr. Paul Sharpe, who is one of the pioneers and leaders in this field. Dr. Paul Sharpe is head of the Department of Craniofacial Development and Stem Cell Biology at the historic King's College London, which is a wellspring of biomedical pioneers and innovation. As department head, Dr. Sharpe leads multiple academic research groups consisting of world-class biomedical researchers aiming to unravel the causes of diseases and translate discoveries into treatments to improve health worldwide. Dr. Sharpe's research focuses on the molecular control of tooth development, dental stem cell biology, and stem-cell-based therapies in clinical dentistry. He's been at this for 30 plus years and counting, publishing over 300 research papers to date. In 2004 Dr. Sharpe was awarded the Craniofacial Biology Research Award by the International Association for Dental Research, in recognition of his contribution to the understanding of how teeth develop. There's no one else better to talk with about this amazing Biotooth technology, which has the potential to restore smiles and improve an incredible amount of lives. In this interview with Dr. Sharpe, we focus on how tooth regeneration research (known as "Biotooth") came to be, its current status, where it's headed in the near future, and what needs to happen for it to become a clinical treatment. In part 1 of 3 of this interview with Dr. Sharpe, we go into how Dr. Sharpe conceived the Biotooth concept and how it works. For parts 2 and 3, please sign up to our mailing list at https://furtherhealth.org for updates on the rest of the interview. For all questions, please reach out to our team at https://furtherhealth.org/contact About Further Health: Further Health believes that biomedical innovation has been and will continue to be one of the major contributors to expanding wellbeing and human health opportunities. Further Health helps you make sense of the most incredible biomedical research projects going on today and how you can contribute to them to help invent the future of health. Visit our website and sign up to our mailing list to learn how. Make sure to follow us on all channels to get the latest updates on inspiring research efforts aiming to help people live healthier for longer. Connect with Further Health: -Sign up for the latest updates from Further Health: https://furtherhealth.org/ -Follow Further Health on TWITTER: https://twitter.com/further_health -Follow Further Health on INSTAGRAM: https://www.instagram.com/furtherhealthproject/ -Follow Further Health on YOUTUBE: https://bit.ly/2XpwdIG -Listen to the PODCAST version of this episode: https://furtherhealth.org/podcast/ Reference(s): -The World Health Organization's Global Oral Health Fact Sheet: https://www.who.int/news-room/fact-sh ...

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